The fire started inside of 1547 Commonwealth Ave. near E. Tremont Avenue just after 5:30 a.m., fire officials say.
It was also reported that at least 150 firefighters were battling the fire.
More than 20 people were injured Tuesday morning when a seven-alarm fire struck an apartment building in the Bronx, a Fire Department of NY spokesman said.
Most of the injuries are believed to be non-life-threatening.
There are twelve apartments above the store.
Flames and smoke could be seen pouring from the building.
One resident told NBC news he fled the building, barefoot and barechested, with his three children into freezing temperatures that dipped as low as minus 10 degrees Celsius (10 degrees Fahrenheit).
"They've all been transported, and they will all be ok, thankfully", he said, noting there were at least nine children among the injured. "By the time we opened the door in the hallway, there was black smoke".
"I woke up my husband, my kids and said listen there's a fire in the building", she said.
Investigators are working to determine the cause of the fire.
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