Clinically, this condition is called "compensated hypogonadism"-"hypogonadism" because the body probably isn't producing testosterone at the appropriate rate, and "compensated" because other hormones have kicked in and gotten testosterone levels to increase. When exposed to levels of ibuprofen similar to that which would be taken orally, the testicle samples produced less testosterone after just 24 hours.
Those who took the ibuprofen were more likely to have indications of testicular problems - including a condition called compensated hypogonadism that affects reproductive health - meaning men are less likely to be able to father a child.
Young men taking ibuprofen saw a coordination between luteinizing hormones (LH) - those that produce testosterone - and the level of ibuprofen in their bloodstream.
Previous research by the team, which focused on pregnant women, had found that the use of Paracetamol and Ibuprofen during pregnancy affected the testicles of male babies.
Those in the ibuprofen group were given two doses of ibuprofen a day. The first group was given a daily 600 milligrams dosage of ibuprofen; the second group was given a placebo.
Researchers conducted a relatively small study that included men aged 18 to 35 and found that those who used the common over-the-counter drug developed hormonal imbalances that can cause a reduction in fertility, CBS news reported.
It is known to increase the risk of heart attacks and stroke if taken regularly in high doses for a long time.
'Therefore it is also of concern that men with compensated hypogonadism may eventually progress to overt primary hypogonadism, which is characterised by low circulating testosterone and prevalent symptoms including reduced libido, reduced muscle mass and strength, and depressed mood and fatigue'.
So researchers wanted to look into what happened in adult males who took ibuprofen, which had the strongest results in the earlier study.
If you are concerned about your levels of testosterone and your ibuprofen use, though, it's worth chatting to your GP so you can get checked out and find a way to deal with chronic aches and pains in a healthy way.
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